MILTENYI BIOTEC 130-041-407 Separation Filters Macs 30UM

( Brand: Miltenyi Biotec ), ( Manufacturer Part Number: 130-041-407 ), ( Part Type: Filter ), ( Intended Use/discipline: Biological Laboratory, Dental Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory ), ( Country Of Origin: United States ), ( Unit Quantity: 21 ), ( Unit Type: Unit ), ( Material: Plastic ), ( Volume: 30um ), ( Additional Search Terms: Surplus Laboratory Benchtop Supplies Consumables )

Review MILTENYI BIOTEC Pre separation Filters Yellow Macs

The **Miltenyi Biotec 130-041-407 21 m Pre-Separation Filters for MACS (Magnetic-Activated Cell Sorting)** are essential components in modern cell processing workflows, designed to ensure the highest purity and integrity of cell suspensions prior to magnetic separation. These high-performance filters are engineered to efficiently remove debris, clumps, and unwanted particles from cell samples, thereby optimizing the performance of MACS-based techniques such as positive and negative selection, depletion, and enrichment of target cell populations. Crafted from a durable, sterile-grade polypropylene material, the filters feature a precise 21 m pore size, which effectively blocks contaminants while allowing viable cells to pass through with minimal shear stress. This pore size is particularly well-suited for applications involving a wide range of cell types, including but not limited to, immune cells, stem cells, and primary cell cultures, where maintaining cell viability and functionality is critical. The filters are pre-sterilized via gamma irradiation, ensuring a clean and contamination-free surface that safeguards the integrity of the cell sample throughout the filtration process. Their compact, disposable design eliminates the need for complex cleaning or sterilization procedures, streamlining workflows and reducing the risk of cross-contamination between experiments. Additionally, the filters are compatible with standard MACS separation protocols, seamlessly integrating into existing laboratory setups that utilize Miltenyi s magnetic cell separation technology. Whether used in research settings for the isolation of rare cell populations or in clinical applications for therapeutic cell processing, these pre-separation filters play a pivotal role in enhancing the efficiency, reproducibility, and reliability of cell sorting procedures. Their thoughtful engineering and adherence to stringent quality standards make them an indispensable tool for laboratories seeking to achieve consistent and high-yield cell separations with minimal operational hassle.

**Pros and Cons of Buying Miltenyi Biotec 130-041-407 (21 m Pre-Separation Filters for MACS)**

### **Pros**

1. **High Quality and Reliability** Miltenyi Biotec is a well-established company in the field of cell separation and magnetic cell sorting. Their products are designed for precision and consistency, which is critical in research and clinical applications.

2. **Compatibility with MACS Systems** These filters are specifically engineered to work seamlessly with Miltenyi s Magnetic-Activated Cell Sorting (MACS) technology, ensuring optimal performance for cell isolation, depletion, or enrichment protocols.

3. **Optimized Pore Size (21 m)** The 21 m pore size is ideal for filtering cell suspensions while retaining larger particles (e.g., cell clumps, debris, or unwanted contaminants). This helps improve downstream purity and yield in experiments.

4. **Easy Integration into Workflow** The filters are designed to fit standard MACS columns and other filtration systems, making them convenient for researchers already using Miltenyi s equipment.

5. **Reduced Contamination** By filtering out debris and aggregates, these filters help minimize contamination in cell cultures or downstream assays, improving experimental reliability.

6. **Cost-Effective for Bulk Use** While individual filters are priced moderately, purchasing in bulk (as suggested by the part number) can reduce per-unit costs, making them economical for labs with high throughput needs.

7. **Compatibility with Various Cell Types** The filters work well with a wide range of cell types commonly used in immunology, stem cell research, and cancer biology, making them versatile for different applications.

8. **Minimal Shearing of Cells** The design of the filters is gentle on cells, reducing stress-induced apoptosis or damage during filtration.

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### **Cons**

1. **Disposable Nature** Like most single-use filtration products, these filters generate waste, which can be costly and environmentally impactful over time. Labs with strict sustainability policies may need to consider alternatives.

2. **Limited Reusability** Unlike some reusable filters, these are designed for single-use only, which may increase long-term expenses if used frequently.

3. **Cost per Use** While bulk purchases help, individual filters can still be expensive compared to generic or lower-cost alternatives, especially for labs with tight budgets.

4. **Potential Clogging** If not used properly (e.g., with highly concentrated or clogged cell suspensions), the filters may become obstructed, requiring additional washing steps or replacement.

5. **Dependence on Miltenyi Ecosystem** If a lab is not already invested in Miltenyi s MACS system, purchasing these filters may not be cost-effective, as they are optimized for compatibility with their equipment.

6. **Storage Requirements** Proper storage (e.g., sterile, sealed packaging) is necessary to maintain sterility, which may require additional space and care.

7. **No Customization Options** The 21 m pore size is fixed, meaning labs with very specific filtration needs (e.g., smaller or larger particles) may need to use additional filters or alternative methods.

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### **Conclusion**

Miltenyi Biotec s 21 m pre-separation filters (130-041-407) are a high-quality, reliable choice for labs using MACS technology. They excel in ensuring cell purity, reducing contamination, and integrating smoothly into existing workflows. However, their disposable nature, cost, and dependency on the Miltenyi system may pose challenges for some users, particularly those with budget constraints or alternative filtration needs.

### **Recommendation**

- **For labs already using Miltenyi MACS systems:** These filters are highly recommended due to their compatibility, performance, and reliability. Bulk purchasing can help mitigate cost concerns.

- **For labs on a tight budget or with alternative filtration needs:** Consider comparing prices with generic or reusable filters (e.g., from other brands like Sartorius or Pall) to see if they meet your quality and cost requirements. If purity and consistency are critical, the Miltenyi filters remain a strong choice despite the higher cost.

- **For sustainability-conscious labs:** Evaluate whether reusable or lower-waste filtration systems could be integrated into the workflow without compromising cell viability or experimental outcomes.

Ultimately, the decision should be based on the lab s specific needs, budget, and existing equipment infrastructure. If MACS compatibility and cell purity are priorities, these filters are a sound investment. Otherwise, exploring alternatives may be worthwhile.

Details:

They fit onto MACS MS, LS, LD, CS, Large Cell, and Whole Blood Columns, as well tubes with a capacity of 5 ml 13 15. One set contains 50 sterile and ready-to-use filters. BIOTECH BARGAINS item for sale. GSR veers 1547 GS 9.4.2 1547 , GSR 1730 9.9.4 1730 New, lot of 21 filters.

Pre-Separation Filters are designed for the easy removal of cell aggregates or large particles from single-cell suspensions to ensure effective magnetic fluorescent labeling, and thus optimal flow within separation columns centimeter.

part #: 130041407 prices

• $97.99-$402.43

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• brand: Miltenyi Biotec
• mpn: 130-041-407
• part type: Filter
• intended use/discipline: Biological Laboratory, Dental Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory
• country of origin: United States
• unit quantity: 21
• unit type: Unit
• material: Plastic
• volume: 30um
• additional search terms: Surplus Laboratory Benchtop Supplies Consumables

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