PYREX CORNING 4320C-5L Glass Wall Round Bottom Boiling Flask 5000ML 45/50

( Brand: Pyrex Corning ), ( Manufacturer Part Number: 4320C-5L ), ( Part Type: Wall ), ( Intended Use/discipline: Biological Laboratory, Dental Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory ), ( Unit Type: Unit ), ( Country Of Origin: United States ), ( Additional Information: Surplus Laboratory Consumable Supplies )

Review PYREX CORNING Glass 5000ml 45/50 Heavy Wall Round Bottom Boiling Flask

The **Corning Pyrex 4320C-5L Glass 5000 mL 45/50 Wall Round Bottom Boiling Flask** is a precision-engineered laboratory glassware essential for demanding chemical synthesis, distillation, and high-temperature reactions. Crafted from **borosilicate glass (Type 3.3)**, this flask exemplifies durability and chemical resistance, ensuring stability even under rigorous conditions, including prolonged exposure to extreme temperatures and aggressive solvents. Its **5-liter capacity (5000 mL)** provides ample volume for large-scale experiments, making it ideal for academic research, pharmaceutical development, or industrial-scale processes where scalability is critical. The **45/50 wall joint** conforms to standard laboratory glassware compatibility, allowing seamless integration with condensers, adapters, and other glassware components, while its **round bottom design** optimizes heat distribution and minimizes hot spots during heating or reflux operations. The thick, **45/50 wall thickness** enhances structural integrity, reducing the risk of cracking under thermal shock or mechanical stress, while its **smooth, polished interior** minimizes residue buildup and ensures consistent reaction efficiency. Whether used in **reflux setups, distillation columns, or high-boiling solvent applications**, this flask delivers exceptional clarity and thermal endurance, making it a cornerstone of reliable laboratory operations. Built to withstand temperatures up to **500 C**, it is perfect for applications requiring precise temperature control, such as **Schlenk reactions, solvent purifications, or large-batch synthesis**. Its **rigid construction and inert properties** also make it a preferred choice for experiments involving corrosive or volatile substances, where traditional plastic or lower-grade glassware would fail. For laboratories prioritizing **longevity, precision, and versatility**, the Corning Pyrex 4320C-5L flask represents an indispensable investment in both performance and safety.

**Pros and Cons of buying a Pyrex Corning 4320C-5L Glass 5000ml 45/50 Wall Round Bottom Boiling Flask**

### **Pros**

1. **Durability and Chemical Resistance** Made from borosilicate glass (Type 3.3), this flask is highly resistant to thermal shock and most common laboratory chemicals, making it suitable for a wide range of applications, including heating, refluxing, and distillation.

2. **High Temperature Tolerance** The borosilicate glass can withstand temperatures up to approximately 500 C (932 F), allowing for high-temperature reactions without risk of cracking or deformation.

3. **Precision and Clarity** The thick 45/50 wall construction ensures structural integrity while maintaining optical clarity, which is essential for monitoring reactions and ensuring accuracy in measurements.

4. **Versatility** The round bottom design is ideal for use with condensers, heating mantles, and other laboratory glassware, making it adaptable for distillation, reflux, and boiling applications.

5. **Long Lifespan** Properly maintained, borosilicate glassware like this flask can last for decades, making it a cost-effective investment for laboratories and serious hobbyists.

6. **Compatibility with Standard Fittings** The standard ground glass joints (typically 24/40 or 50/50) allow for easy connection to other glassware, such as adapters, condensers, and funnels.

7. **Safety** Unlike plastic or lower-quality glassware, borosilicate glass does not leach contaminants or degrade over time, reducing health and safety risks.

---

### **Cons**

1. **Fragility Despite Durability** While borosilicate glass is more resistant to thermal shock than soda-lime glass, it is still brittle. Dropping or mishandling can cause it to shatter, potentially leading to injury or contamination.

2. **Heavy Weight** The 5-liter size and thick walls make this flask significantly heavier than plastic alternatives, which can be cumbersome to handle, especially for extended periods.

3. **Cost** Borosilicate glassware is more expensive than standard soda-lime glass or plastic alternatives. For occasional or low-budget use, this may not be justified.

4. **Maintenance Requirements** Glassware must be cleaned thoroughly after use to prevent residue buildup, which can affect future reactions. Scratches or pitting from improper cleaning can also weaken the glass over time.

5. **Limited Flexibility** Unlike plastic or flexible containers, this flask cannot be bent or deformed to fit unconventional setups. It requires precise alignment with other glassware for proper function.

6. **Potential for Contamination** If not stored properly (e.g., covered or in a dust-free environment), dust, moisture, or chemical residues can accumulate inside, compromising the purity of subsequent experiments.

7. **Replacement Parts and Fittings** While standard, some older or specialized setups may require non-standard joints, which could necessitate purchasing additional adapters or seals.

---

### **Conclusion**

The **Pyrex Corning 4320C-5L borosilicate glass round bottom flask** is an excellent investment for laboratories, chemists, or serious hobbyists who require **durability, chemical resistance, and high-temperature performance**. Its superior quality justifies the higher cost for applications involving **distillation, reflux, or precise heating processes**. However, for **budget-conscious users, occasional use, or non-chemical applications**, the expense and weight may outweigh the benefits.

If you prioritize **longevity, safety, and reliability** in a glassware piece that will serve for years, this flask is highly recommended. For temporary or low-stakes projects, consider whether a **lower-cost alternative** (e.g., plastic or soda-lime glass) would suffice.

- You need **high-temperature and chemical resistance** for serious laboratory work.

- You require **long-term durability** and plan to use it frequently.

- You are working with **precise reactions** where glass clarity and structural integrity are critical.

- You are on a **tight budget** and the flask will not be used regularly.

- You lack proper storage or handling precautions, risking damage.

- You can achieve your goals with **more affordable alternatives**.

Details:

No chips or cracks throughout. Please see pictures for details. Used item in excellent condition.

part #: 4320c5l prices

• $325.37-$470.00

specifications plasticwarelabsuppy:

• brand: Pyrex Corning
• mpn: 4320c-5l
• part type: Wall
• intended use/discipline: Biological Laboratory, Dental Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory
• unit type: Unit
• country of origin: United States
• additional information: Surplus Laboratory Consumable Supplies

payments plasticwarelabsuppy:

• wallet: Google-pay
• other
• credit card: Discover

seller plasticwarelabsuppy:

• # reviews: 7545
• rating: 99.9%
• city: Cotati, California

general plasticwarelabsuppy:

• Medical, Lab Dental Supplies > Glassware Plasticware > Other Medical Lab Glassware
• condition: Used

shipping plasticwarelabsuppy:

• transit: 5-12 Days
• carrier: FedEx
• type: Fixed
• service: Standard, FedEx 2Day, FedEx Standard Overnight
• class: Standard, Expedited, One-day
• cost: $0.00

returns plasticwarelabsuppy:

• method: Money back
• paid by: Seller
• policy: Returns Accepted
• time: 30 Days

offer plasticwarelabsuppy:

• options: Ship-to-home
• sold: 0
• quantity: 1
• started: March 13, 2026
• availability: In Stock

Pyrex Corning 4320C-5L Is Similar To:

• 5420-500 5420-800 Pyrex Nos Kjeldahl Lab Flask Lot Long Neck Round (24.7% similar) These are new from old stock. Pyrex 5420 skeletal flask lot 500ML 800ML. Lot of brisket heat-resistant Pyrex skeletal flasks 5 total...(May 31st, 2019)
• 8090 Pyrex Vintage Glass Scientific Mohr Pipette Pipet Pfeiffer In Box (28% similar) Box has some signs of wear includes 28 pieces. Pipettes are long. 1 has the end chipped. Lot of 28 vintage glass scientific 1ML More pipette piper Pyrex perfecta 8090MADE in upcoming with the original proffer box. Only 3 has some signs of wear...(January 27th, 2019)
• 1000-250 Pyrex Corning Vista Beaker (35.1% similar) Pyrex brand, 150ML wide mouth beaker, glass is clear with no etching, chips or cracks would make unique lamp, light chandelier terrarium, aquarium...(December 24th, 2018)
• 1000-400 Corning Pyrex Glass Graduated Low Form Griffin Beaker (35.5% similar) 400ML low form Pyrex griffin beaker with spout, double scale, graduated convenient graduated metric scale for estimating content graduation range: 25-325ML graduation interval: 25ML height : 110MM approx outer diameter: 77MM extra large marking spot...(November 27th, 2018)
• 12000 Ml Pyrex Used Round Bottom Flask Plus Supersize Me Options (37.8% similar) Back by sending a photo e-mail of the item you bought in your lab. Is the safest choice for buying used laboratory equipment. Why take a risk. Shipping is usually by us. Shipping is by ups ground or FedEx us. There is a choice, you don't have to feel like you're dealing with network syndicate ...(November 8th, 2018)
• 12344568 Pyrex Test Tubes Glass Thin Walled Dozen (35.9% similar) There is one missing. There are 35 test tubes...(December 23rd, 2018)
• 1235656789 China Glass Blowing Tubing Pink Mm Purple Pieces Total Pyrex (24% similar) ...(October 21st, 2018)
• 1260-250 Corning Pyrex Ml Heavy Wall Plain Top Centrifuge Bottle (42% similar) Clean and chip free Corning Pyrex heavy wall plain top centrifuge bottle catalog number ml...(November 22nd, 2018)
• 1260-500 Pyrex Corning Ml Centrifuge Heavy Wall Bottle (49.6% similar) ...(September 22nd, 2018)
• 1367-160 Corning Pyrex Narrow Mouth Milk Dilution Bottles (33.8% similar) This listing is for 5 bottles and caps. 5 Corning Pyrex no narrow mouth milk dilution bottles 160ML there are a few that have light faded writing on the labels. Bottles are in good condition...(October 6th, 2018)
• 1395-1l Pyrex Corning Glass Graduated Around Media Storage Bottle (45.8% similar) Price is for each one. Corning Pyrex mixed media glass storage bottles, 1000ML made in Germany trace code excellent condition I will combine shipping if you purchase more than one...(October 14th, 2018)