
( Brand: Hamilton ), ( Manufacturer Part Number: 87943 ), ( Model: 65RNR ), ( Part Type: Gauge )
The **Hamilton 87943 5 L 65RNR Syringe with 22G 5/10 Point Needle** is a precision-engineered, high-performance syringe designed for demanding applications in laboratory research, pharmaceutical development, and advanced biotechnology. This ultra-low-volume syringe combines Hamilton s legendary reliability with cutting-edge fluidics technology, making it an indispensable tool for scientists and technicians who require unparalleled accuracy, consistency, and ease of use in microdispensing tasks. The **5 L capacity** allows for precise handling of minute sample volumes, minimizing waste while maximizing experimental efficiency, particularly in fields such as genomics, proteomics, and high-throughput screening. The **65RNR (Rotating Needle, Reverse Thread)** design ensures secure attachment and detachment of the needle without cross-contamination, a critical feature when working with hazardous or precious samples. The **22-gauge needle**, with its **5/10 point tip**, strikes an optimal balance between precision and ease of insertion, reducing tissue damage in biological applications while maintaining the fine control necessary for delicate pipetting tasks. Constructed from high-quality stainless steel and featuring Hamilton s signature **glass-lined plunger**, this syringe delivers exceptional resistance to corrosion and chemical compatibility, ensuring long-term durability even when exposed to aggressive solvents, buffers, or organic reagents. The **low dead volume** and **smooth, frictionless plunger action** eliminate air bubbles and ensure consistent dispensing, while the **ergonomic design** allows for comfortable, fatigue-free handling during extended use. Whether used in automated liquid handling systems, manual microdispensing, or high-precision injections, this syringe exemplifies Hamilton s commitment to innovation and precision, making it a trusted choice for researchers who demand nothing less than perfection in their fluidic applications.
### **Pros and Cons of buying a Hamilton 87943 5 L 65RNR Syringe (22G, 51 Point)**
#### **Pros:**1. **Precision and Accuracy** The Hamilton 87943 is designed for high-precision liquid handling, making it ideal for applications requiring minimal volume dispensing (5 L). Its tight tolerances ensure consistent performance, reducing errors in experiments.
2. **Low Dead Volume** The 65RNR (65R) needle configuration minimizes dead volume, which is critical in analytical chemistry, biochemistry, and pharmaceutical applications where sample loss must be minimized.
3. **Durability and Reusability** Hamilton syringes are built for durability, allowing for repeated use without significant degradation. This makes them cost-effective over time, especially in high-throughput laboratories.
4. **Compatibility with Automation** The syringe is designed to work seamlessly with automated liquid handling systems, improving efficiency in robotic workflows.
5. **Consistency in Flow Rate** The 22-gauge needle with a 51 bevel ensures smooth fluid flow, reducing clogging and improving reliability in delicate applications like HPLC or GC sample injections.
6. **Brand Reputation** Hamilton is a trusted name in precision fluid handling, known for quality control and reliability in research and industrial settings.
7. **Versatility** Suitable for a wide range of applications, including chromatography, drug delivery studies, and microvolume dispensing.
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#### **Cons:**1. **High Initial Cost** Compared to disposable syringes, Hamilton syringes are significantly more expensive upfront, which may be a barrier for small labs or budget-conscious users.
2. **Maintenance Requirements** Unlike disposable syringes, Hamilton syringes require regular cleaning and maintenance to prevent contamination and ensure optimal performance. Neglecting maintenance can lead to inaccurate results.
3. **Limited Volume Range** At just 5 L, this syringe is specialized for microvolume applications. Larger volume needs would require additional syringes, increasing costs.
4. **Needle Wear Over Time** Frequent use can cause wear on the needle tip, potentially affecting precision. Replacement needles may be required periodically.
5. **Not Ideal for High-Viscosity Samples** While the 22G needle works well for most liquids, highly viscous samples may clog or require additional force, reducing ease of use.
6. **Learning Curve for New Users** Proper handling and calibration may require training, especially for those unfamiliar with precision syringes.
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### **Conclusion:**The **Hamilton 87943 5 L 65RNR syringe** is an excellent choice for laboratories and applications requiring **ultra-high precision, low dead volume, and repeatability**. Its durability and compatibility with automation make it a valuable investment for research, pharmaceutical, and analytical settings where accuracy is critical.
However, the **high upfront cost, maintenance needs, and specialized use case** may not justify its purchase for casual or low-volume users. If budget is a concern, disposable syringes or lower-cost alternatives might suffice for less demanding applications.
### **Recommendation:**- **Buy if:** You work in a **high-precision laboratory** (e.g., chromatography, microvolume dispensing, pharmaceutical research) where accuracy and consistency are non-negotiable, and you can justify the long-term cost savings from reduced errors and increased efficiency.
- **Avoid if:** You require a **budget-friendly, disposable option** or work with **low-volume, non-critical applications** where the cost and maintenance overhead are unnecessary.
For most **serious research or industrial settings**, the Hamilton syringe is a worthwhile investment. For casual or low-budget users, alternatives should be considered.