ALWSCI C0000149 Hplc Slit Lids Ptfe Silicone Liner 663274558204 9-425

( Brand: Alwsci ), ( Manufacturer Part Number: C0000149 ), ( Part Type: Lid Liner ), ( Color: Blue Lids Pre Slit Blue Ptfe White Silicone Liner ), ( Packageheight: 15 ), ( Packagelength: 112 ), ( Packagewidth: 111 ), ( UPC: 663274558204 )

Review ALWSCI Hplc Pre slit Blue Lids Ptfe White Silicone Liner

The **ALWSCI C0000149 HPLC Pre-Slit 9 425 m Lids with PTFE Silicone Liner** is a high-performance, precision-engineered accessory designed to enhance the efficiency, reliability, and longevity of High-Performance Liquid Chromatography (HPLC) systems. These specialized vial caps feature a unique pre-slit design, allowing for controlled headspace venting while maintaining an airtight seal when not in use, which is critical for preventing contamination, solvent evaporation, and pressure buildup in sealed sample vials. The slit dimensions ranging from **9 to 425 micrometers** provide flexibility to accommodate varying analytical requirements, from low-pressure applications where minimal venting is needed to high-pressure or volatile solvent systems where regulated gas exchange is essential. Crafted from high-quality materials, the caps incorporate a **PTFE (polytetrafluoroethylene) silicone liner**, a combination that ensures exceptional chemical resistance, low extractables, and compatibility with a broad spectrum of solvents, including organic solvents, acids, bases, and polar solvents. The PTFE liner minimizes adsorption of analytes, reducing peak tailing and improving chromatographic resolution, while the silicone backing provides a durable, flexible seal that resists deformation under repeated use. Ideal for applications in pharmaceutical development, environmental testing, food safety analysis, and biopharmaceutical research, these lids are engineered to meet stringent industry standards for cleanliness and performance. Their ergonomic design allows for easy installation and removal, reducing the risk of cross-contamination during sample handling, while the precision-machined slit ensures consistent venting performance across thousands of uses. Whether used in automated sampling systems or manual workflows, these HPLC vial caps deliver a seamless integration with standard 9 mm or 4 mm vial formats, making them a versatile and indispensable component for laboratories seeking both precision and reliability in their chromatographic analyses.

### **Pros and Cons of buying a ALSWC I0000149 HPLC Pre-Slit 9-425 Lid with PTFE Silicone Liner**

1. **Compatibility with HPLC Systems** Designed specifically for high-performance liquid chromatography, ensuring proper sealing and performance with standard HPLC setups.

2. **PTFE Silicone Liner** The PTFE (polytetrafluoroethylene) liner provides chemical resistance, reducing contamination risks from solvents and sample matrices. The silicone backing adds flexibility and durability.

3. **Pre-Slit Design** The pre-slit feature allows for precise venting, preventing pressure buildup in the vial, which is critical for accurate injections and preventing leaks.

4. **Wide Temperature Range** Suitable for both ambient and elevated temperatures, making it versatile for different HPLC applications, including gradient elution and high-temperature analyses.

5. **Reusable and Cost-Effective** Unlike disposable caps, this lid can be reused multiple times, reducing long-term expenses.

6. **Standardized Size (9 mm)** Fits standard 9 mm HPLC vials, ensuring compatibility with most autosamplers and injection systems.

7. **Durability** The construction appears robust, reducing the likelihood of premature wear or failure, which is essential for high-throughput laboratories.

8. **Reduced Sample Evaporation** The tight seal minimizes headspace exposure, helping maintain sample integrity over time.

9. **Easy Installation** Designed for quick and secure attachment to HPLC vials, reducing downtime during sample preparation.

10. **Manufacturer Support** Purchasing from a reputable supplier (e.g., Agilent, Waters, or a trusted HPLC accessory brand) ensures quality control and potential warranty coverage.

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1. **Potential Compatibility Issues** While designed for HPLC, some older or non-standard autosamplers may not accommodate the pre-slit or PTFE liner perfectly, requiring additional adapters or adjustments.

2. **Cost Relative to Disposable Caps** Though reusable, the upfront cost may be higher than single-use caps, though it pays off over time with repeated use.

3. **Maintenance Requirements** Over time, the PTFE liner may degrade or become contaminated, necessitating periodic cleaning or replacement to maintain performance.

4. **Limited Customization** The pre-slit design is fixed, meaning it cannot be adjusted for different venting needs, which may be a limitation for specialized applications.

5. **Potential for Cross-Contamination** If not cleaned thoroughly between uses, residues from previous samples could carry over, affecting subsequent analyses.

6. **Not Universal for All Vial Sizes** While it fits 9 mm vials, it may not be compatible with other vial sizes (e.g., 4 mm or 12 mm), requiring separate purchases.

7. **Durability Concerns with Aggressive Solvents** While PTFE is chemically resistant, prolonged exposure to highly corrosive solvents (e.g., certain acids or bases) could degrade the liner over time.

8. **Potential for Misalignment** If not installed correctly, the lid may not seal properly, leading to leaks or inaccurate injections.

9. **Supplier Dependence** Quality may vary depending on the brand or supplier; purchasing from lesser-known manufacturers could risk inferior performance or compatibility issues.

10. **Warranty Limitations** Some suppliers may offer limited warranties, and damage from improper use (e.g., excessive force during installation) may void coverage.

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### **Conclusion**

The **ALSWC I0000149 HPLC Pre-Slit 9-425 Lid with PTFE Silicone Liner** is a high-quality, reusable accessory tailored for HPLC applications. Its chemical resistance, venting design, and compatibility with standard vials make it a practical choice for laboratories prioritizing accuracy, durability, and cost efficiency over time. However, its higher initial cost, maintenance needs, and potential compatibility issues with non-standard systems may pose challenges depending on the specific workflow.

For laboratories performing routine HPLC analyses with standard 9 mm vials and autosamplers, this lid is **highly recommended** due to its reliability and long-term cost savings. Conversely, users with highly specialized or non-standard setups may need to verify compatibility or consider alternative solutions.

- You use standard 9 mm HPLC vials and autosamplers.

- You prioritize chemical resistance and long-term durability.

- Your budget allows for the upfront investment in a reusable, high-quality component.

- Your system requires non-standard vial sizes or configurations.

- You frequently use highly aggressive solvents that may degrade the PTFE liner.

- Cost is a critical factor, and disposable caps are more feasible for your workflow.

Details:

ALWSCI HPLC Pre-Slit 9-425 Blue Lids Pre-slit,Blue PTFE White Silicone Liner. With Blue PTFE Faced White silicone ,pre-slit Liner. Manufactured with Blue Polypropylene 9-425 9mm type threaded vial caps. Suitable for 1.5 ml, 1.8 2 ml 9-425 vials.

Blue screw cap with hole PTFE / Silicone septa Compatible most Auto sampler vials. Pre-slit liner, more easy to pierce, protect injection needle.

part #: c0000149 prices

• $25.99-$94.41

specifications plasticwarelabsuppy:

• brand: Alwsci
• mpn: C0000149
• part type: Lid Liner
• color: Blue Lids Pre Slit Blue Ptfe White Silicone Liner
• packageheight: 15
• packagelength: 112
• packagewidth: 111
• upc: 663274558204

general plasticwarelabsuppy:

• condition: New
• Medical, Lab Dental Supplies > Glassware Plasticware > Other Medical Lab Glassware

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• # reviews: 35
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• city: Denver, Colorado

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• options: Ship-to-home
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• availability: In Stock
• quantity: 1
• started: March 13, 2026

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