CHEMGLASS CG-1860-03 Glass Frit Solid Phase Peptide Vessel 50ML Synthesis

( Brand: Chemglass ), ( Manufacturer Part Number: CG-1860-03 ), ( Intended Use/discipline: Biological Laboratory, Dental Laboratory, Microbiological Laboratory, Medical Laboratory, Physical Laboratory ), ( Country Of Origin: United States ), ( Unit Type: Unit ), ( Additional Information: Surplus Laboratory Consumable Supplies )

Review CHEMGLASS Glass 50ml Frit Solid Phase Peptide Synthesis Vessel

The **Chemglass CG-1860-03 Glass 50 mL Frit Solid Phase Peptide Synthesis Vessel** is a precision-engineered laboratory tool meticulously designed for high-efficiency solid-phase peptide synthesis (SPPS), offering researchers and chemists a robust, reusable, and chemically inert platform for peptide assembly. Constructed from high-quality borosilicate glass (Type I, meeting USP Class A standards), this vessel combines durability with exceptional clarity, allowing for real-time monitoring of reactions under UV light or visual inspection without compromising sterility. The unique frit design comprising a fine, uniform glass filter at the base enables rapid and efficient washing, filtration, and resin support separation while minimizing peptide loss during processing. With a generous 50 mL working capacity, this vessel accommodates scalable synthesis protocols, from small-scale peptide production to intermediate batch processing, making it ideal for both academic research and industrial applications. The vessel s screw-cap closure, equipped with a Teflon-lined septum, ensures an airtight seal to prevent contamination while allowing for easy introduction of solvents, reagents, or gases via syringe. Its ergonomic, wide-mouth design facilitates effortless loading and unloading of resin beads, reducing user fatigue during prolonged synthesis cycles. Additionally, the vessel s compatibility with standard SPPS accessories such as shakers, fume hoods, and vacuum filtration setups enhances its versatility, enabling seamless integration into automated or manual workflows. Whether employed for the synthesis of complex peptides, peptide libraries, or biochemical conjugates, the CG-1860-03 delivers reliability, reproducibility, and chemical resistance, making it an indispensable asset for laboratories prioritizing purity, efficiency, and long-term performance in peptide chemistry.

**Pros and Cons of buying a Chemglass CG-1860-03 Glass 50mL Frit Solid Phase Peptide Synthesis Vessel**

1. **High-Quality Glass Construction** The vessel is made from borosilicate glass, which is chemically resistant, durable, and suitable for harsh organic solvents and acidic/basic conditions commonly used in peptide synthesis. This minimizes the risk of contamination or degradation of reagents.

2. **Frit Design for Efficient Filtration** The frit (glass filter) allows for gentle filtration of reaction mixtures without clogging, reducing the need for external filtration equipment. This simplifies workflows, especially in manual peptide synthesis.

3. **Compatibility with Standard SPPS Techniques** The vessel is designed specifically for solid-phase peptide synthesis (SPPS), making it ideal for researchers and labs performing manual coupling, deprotection, and washing steps. It fits standard SPPS protocols without requiring modifications.

4. **Reusable and Cost-Effective** Unlike disposable plastic or polypropylene vessels, this glass vessel can be reused multiple times with proper cleaning, reducing long-term expenses. Glass is also easier to sterilize and reuse in academic or industrial settings.

5. **Chemical Resistance** The borosilicate glass resists most organic solvents (e.g., DMF, DCM, NMP), acids (e.g., TFA), and bases (e.g., DIPEA), which are critical for peptide synthesis. This ensures the integrity of reactions and prevents leaching of contaminants.

6. **Compatibility with Common Equipment** The vessel can be used with standard SPPS accessories like syringes, pipettes, and rotary evaporators, making it versatile for various lab setups.

7. **Durability and Longevity** Glass vessels are less prone to cracking or warping compared to plastic alternatives, especially when exposed to repeated heating or cooling cycles.

8. **Transparency for Visual Monitoring** The clear glass allows users to visually monitor reaction progress, color changes, or the presence of precipitates, which can be useful for troubleshooting.

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1. **Fragility Compared to Plastic** While borosilicate glass is durable, it is still more prone to breakage than plastic or polypropylene vessels, especially if dropped or subjected to thermal shock (e.g., rapid temperature changes). This requires careful handling.

2. **Heavier Than Plastic Alternatives** Glass vessels are heavier, which can be cumbersome for labs performing large-scale or high-throughput synthesis. This may also increase shipping costs if ordering multiple units.

3. **Cleaning and Maintenance** Glass requires thorough cleaning with strong detergents or organic solvents to remove residual peptides, reagents, or salts. Improper cleaning can lead to cross-contamination between syntheses. Some stubborn residues may require sonication or extended washing.

4. **Limited Autoclave Compatibility** While borosilicate glass can withstand autoclaving, prolonged exposure to high temperatures and pressure may weaken the vessel over time. Some labs prefer disposable alternatives for sterilization to avoid wear and tear.

5. **Cost Relative to Disposable Options** Although reusable, the initial purchase price of a high-quality glass vessel may be higher than disposable polypropylene or glassware. However, this cost is often justified by long-term savings.

6. **Potential for Scratches or Damage** Glass surfaces can develop scratches from abrasive cleaning tools or pipette tips, which may affect filtration efficiency or introduce micro-contamination. This requires gentle handling and appropriate cleaning techniques.

7. **Not Ideal for High-Pressure Applications** Unlike some plastic vessels, glass is not designed for high-pressure reactions (e.g., microwave-assisted synthesis under pressure). It is best suited for standard atmospheric or low-pressure SPPS.

8. **Limited Availability of Replacement Parts** If the frit becomes damaged or clogged, replacing it may be difficult or require sourcing from the manufacturer, potentially causing downtime.

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The **Chemglass CG-1860-03 50mL frit glass vessel** is an excellent choice for researchers and labs engaged in **solid-phase peptide synthesis (SPPS)**, particularly those prioritizing **chemical resistance, durability, and reusability**. Its frit design simplifies filtration, reducing the need for external equipment, while borosilicate glass ensures compatibility with a wide range of solvents and reaction conditions. The vessel is well-suited for **academic, industrial, or small-scale peptide synthesis** where long-term use and reliability are critical.

However, its **fragility, weight, and maintenance requirements** may pose challenges in high-throughput or high-risk environments. If **durability and chemical resistance** are the top priorities, this vessel is highly recommended. For labs with limited budgets or those performing **disposable-based workflows**, alternative materials (e.g., polypropylene or disposable glassware) might be considered. Ultimately, the **cost-effectiveness and performance** of this vessel make it a strong investment for serious peptide chemists.

- You perform **manual or semi-automated SPPS** and need a **reliable, reusable vessel**.

- Your workflow involves **harsh solvents, acids, or bases**, and you require **chemical resistance**.

- You prioritize **filtration efficiency** without additional equipment.

- You are working in an **academic or industrial setting** where long-term use justifies the initial cost.

- You frequently handle **large volumes or high-throughput synthesis**, where weight and fragility may be concerns.

- Your budget is limited, and you can justify disposable vessels for cost savings.

- You require **high-pressure or microwave-assisted synthesis**, which may not be suitable for glass vessels.

For most **serious peptide chemists**, this vessel is a **high-quality, versatile tool** that enhances efficiency and reduces long-term expenses.

Details:

No chips or cracks throughout. See pictures for details. GSR veers 1730 GS 9.9.4 1730 Used item in great condition. No cap included.

part #: cg186003 price

• $62.99

specifications plasticwarelabsuppy:

• brand: Chemglass
• mpn: Cg-1860-03
• intended use/discipline: Biological Laboratory, Dental Laboratory, Microbiological Laboratory, Medical Laboratory, Physical Laboratory
• country of origin: United States
• unit type: Unit
• additional information: Surplus Laboratory Consumable Supplies

shipping plasticwarelabsuppy:

• carrier: USPS, FedEx
• transit: 3-8 Days
• class: Standard, Expedited, One-day
• service: USPS First Class, FedEx 2Day, FedEx Standard Overnight
• cost: $0.00
• type: Fixed

general plasticwarelabsuppy:

• condition: Used
• Medical, Lab Dental Supplies > Glassware Plasticware > Other Medical Lab Glassware

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• time: 30 Days
• method: Money back
• paid by: Seller
• policy: Returns Accepted

seller plasticwarelabsuppy:

• city: Cotati, California
• rating: 99.9%
• # reviews: 7609

offer plasticwarelabsuppy:

• sold: 0
• options: Ship-to-home
• availability: In Stock
• quantity: 1
• started: March 24, 2026

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