
( Brand: Millipore ), ( Manufacturer Part Number: XX1012500 ), ( Part Type: Vacuum Filter ), ( Country Of Origin: United States ), ( Intended Use/discipline: Biological Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory, Chemistry Laboratory )
The **Millipore XX1012500 Pyrex 15 mL Vacuum Filter Microfiltration Frit (25 mm)** is a precision-engineered laboratory accessory designed for efficient and reliable microfiltration applications, ideal for researchers, biologists, chemists, and analytical labs requiring high-performance filtration with uncompromising clarity and durability. Crafted from high-quality **Pyrex borosilicate glass (Type 3.3)**, this frit combines exceptional thermal and chemical resistance with optical transparency, ensuring consistent performance across a wide range of experiments from sterile filtration and sample preparation to the removal of particulate contaminants in liquid samples. The **25 mm diameter** design provides a balanced filtration area, optimizing flow rates while maintaining precision, making it suitable for both routine and high-throughput laboratory workflows.
At the heart of this frit lies a **microfiltration membrane structure**, engineered to retain particles as small as **0.1 m** (depending on the specific membrane type used), enabling the separation of microorganisms, colloids, and fine particulates from solutions with remarkable efficiency. The **vacuum-compatible design** allows for rapid filtration under reduced pressure, significantly accelerating processing times compared to gravity filtration methods, while the **15 mL capacity** offers versatility for small-scale applications, including cell culture media sterilization, buffer clarification, and the preparation of samples for spectroscopy or chromatography. The frit s **smooth, glass surface** minimizes adsorption of analytes, preserving the integrity of sensitive biological or chemical samples, and its compatibility with standard **Millipore vacuum filtration systems** ensures seamless integration into existing lab setups.
Beyond its functional excellence, the **XX1012500 frit** is built to withstand the rigors of laboratory use, including repeated autoclaving (up to **121 C**) and exposure to a broad spectrum of solvents, acids, and bases, making it a durable investment for demanding environments. Its **clear, uncoated glass construction** allows for visual confirmation of filtration progress, reducing the risk of clogging or incomplete processing, while the **precision-molded frit surface** ensures uniform pore distribution for consistent filtration performance. Whether used in molecular biology for plasmid DNA purification, microbiology for bacterial filtration, or analytical chemistry for sample pre-treatment, this frit delivers the reliability and precision required to maintain the highest standards of experimental integrity. Its compatibility with **Millipore s extensive range of microfiltration membranes** further enhances its adaptability, allowing users to select the optimal pore size and material (e.g., cellulose acetate, nylon, or PES) for their specific application. In summary, the **Millipore XX1012500 Pyrex 15 mL Vacuum Filter Frit** is an indispensable tool for laboratories prioritizing efficiency, accuracy, and long-term durability in their filtration processes.
**Pros and Cons of buying a Millipore XX1012500 Pyrex 15 mL Vacuum Filter Microfiltration Frit (25 mm)**
### **Pros:**1. **Material Quality and Durability** The Pyrex glass construction is chemically resistant, heat-resistant, and durable, making it suitable for a wide range of laboratory applications, including microfiltration, filtration of corrosive or high-temperature samples, and repeated use without degradation.
2. **Compatibility with Vacuum Filtration Systems** Designed to fit standard vacuum filtration setups, it ensures efficient and controlled filtration processes, reducing manual effort and improving workflow efficiency.
3. **Microfiltration Efficiency** The frit is optimized for microfiltration (typically 0.1 10 m pore sizes, depending on the specific filter used), allowing for the removal of bacteria, particles, and other contaminants while retaining larger molecules or cells.
4. **Versatility in Applications** Suitable for various laboratory tasks, including sample preparation, sterile filtration, cell culture media filtration, and pre-filtration before further analysis (e.g., HPLC, GC, or microbiological testing).
5. **Compatibility with Common Solvents and Reagents** Pyrex glass is inert to most acids, bases, and organic solvents, making it ideal for handling aggressive or volatile substances without risking contamination or degradation.
6. **Easy to Clean and Reuse** Glass components are easier to clean thoroughly compared to plastic alternatives, reducing the risk of carryover contamination between experiments. It can be autoclaved or cleaned with harsh detergents if needed.
7. **Standardized Size (25 mm)** The 25 mm diameter is a common size in laboratory filtration, making it easy to find compatible filters, adapters, and replacement parts.
8. **Transparency for Visual Inspection** The glass body allows for visual monitoring of the filtration process, ensuring clogging or incomplete filtration can be detected early.
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### **Cons:**1. **Fragility Compared to Plastic** While durable, Pyrex glass is still more prone to breakage than plastic alternatives, especially if dropped or mishandled. This increases the risk of injury and potential contamination if the glass shatters.
2. **Weight and Bulkiness** Glass components are heavier than plastic, which can make handling and storage less convenient, particularly in large quantities or fieldwork settings.
3. **Limited Temperature Range for Some Filters** While Pyrex itself is heat-resistant, certain microfiltration membranes (e.g., some polymer-based filters) may have temperature limitations that restrict their use in high-temperature applications.
4. **Cost** Glass filtration systems are generally more expensive than plastic alternatives, which may be a consideration for budget-conscious laboratories or small-scale users.
5. **Potential for Glass Contamination** Even with careful handling, glass surfaces can introduce particulate contamination if not cleaned properly, though this is less of an issue than with plastic.
6. **Incompatibility with Some Membrane Types** Some advanced or specialized filtration membranes (e.g., certain hydrophobic or charged membranes) may not be compatible with this frit design, requiring additional adapters or alternative setups.
7. **Maintenance Overhead** Glass requires more careful handling and cleaning compared to disposable plastic systems, which may not be ideal for high-throughput or disposable workflows.
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### **Conclusion:**The **Millipore XX1012500 Pyrex 15 mL vacuum filter frit** is a high-quality, versatile tool for microfiltration in laboratory settings where durability, chemical resistance, and compatibility with a wide range of samples are priorities. Its Pyrex construction ensures longevity and reliability, making it ideal for applications involving aggressive reagents, high temperatures, or repeated use. However, its fragility, higher cost, and heavier weight may make it less suitable for fieldwork, high-throughput disposable workflows, or environments where breakage is a significant risk.
### **Recommendation:** - **Buy if:**- You require a durable, reusable filtration system for routine laboratory use (e.g., cell culture, sample prep, sterile filtration).
- Your workflow involves corrosive solvents, high temperatures, or repeated cleaning cycles.
- You prioritize glass s chemical inertness and transparency over convenience.
- You are working with standard microfiltration membranes (0.1 10 m) and have a vacuum filtration setup.
- **Consider alternatives if:**- You need a disposable or lightweight system (e.g., plastic vacuum filtration units).
- Your budget is limited, and you can use a lower-cost plastic alternative for less demanding applications.
- You frequently work in field settings where fragility is a concern.
- You require specialized membranes (e.g., ultra-low-binding or hydrophobic filters) that may not fit seamlessly with this frit.
For most standard laboratory microfiltration needs, this frit is a **strong, reliable choice** especially when paired with compatible Millipore filters (e.g., mixed cellulose ester or polyethersulfone membranes). If cost or fragility is a major concern, evaluate whether a plastic alternative (e.g., Corning or Nalgene vacuum filters) would suffice for your specific application.
5 outlet stopper for standard 125 mL filtering flask perforated silicone, Tags / keywords: 14/20 glass joint, frit gritted sauntered glass, 40/35, Erlenmeyer flask, membrane filters, lab pyrex Millipore Duran, Poetics, Millipore Sigma, Gilman, filter apparatus Buckner funnels, nitrocellulose, biology, chemistry, science, DNA, RNA, pulmonary critical care, etc. Quantitative determination of elemental chlorine, nitrogen and sulfur in a sample standard taper pyrex brisket glass, Mex, ST ground glass joint. Millipore specs hydrogen oxygen. Tomas Philadelphia.
25mm, Filtration area 2.5 cm2, Funnel capacity 15 mL, Fitting inlet funnel, No. Millipore / Pyrex Delaware 93705, 15ml Vacuum Filter Microfiltration, LOT of TEN pieces, Equivalent to current catalog # x1012500 Millipore Glass Micro analysis Holder - Kit, x1002503 equivalent 25mm spring clamps, Lot includes everything pictured: FOUR frit filters, THREE column funnels, and clamps. Soluble insoluble, dissolve. Plc CPR pct thermonuclear Thermos cycle Maj research corning pyrex wool fiber caffeine.
Bundle multiple items in one order for combined shipping discount. Analytical procedures for the flask combustion method. The gritted glass is approximately 20mm diameter, with 30mm diameter flange, Pyrex Brisket Lab Glass, Millipore specs: height 15.2 cm 6 in. Diameter 2.5 0.98 Filter diam. FAST USA shipping via USPS.