CHEMGLASS CG-1860-05 Glass Frit Solid Phase Peptide Vessel 500ML Synthesis CG-1860-15
( Brand: Chemglass ), ( Manufacturer Part Number: CG-1860-05 ), ( Intended Use/discipline: Biological Laboratory, Dental Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory ), ( Unit Type: Unit ), ( Country Of Origin: United States ), ( Additional Information: Surplus Laboratory Consumable Supplies )
Review CHEMGLASS Glass 500ml Frit Solid Phase Peptide Synthesis Vessel
The **Chemglass CG-1860-05 and CG-1860-15 Glass Frit Solid Phase Peptide Synthesis Vessels** are precision-engineered, high-performance reaction vessels designed specifically for the demanding requirements of solid-phase peptide synthesis (SPPS). Crafted from borosilicate glass (Type 1, Class A), these vessels combine durability, chemical resistance, and optical clarity to provide an ideal platform for efficient peptide synthesis, purification, and analytical procedures. The **CG-1860-05** features a 500 mL capacity, while the **CG-1860-15** scales up to a 1500 mL volume, accommodating larger-scale syntheses without compromising on functionality. Both models incorporate a **fritted glass sintered disc** at the base, ensuring uniform fluid distribution and gentle filtration during washing, coupling, and deprotection steps critical for maintaining the integrity of delicate peptide chains while minimizing mechanical stress on resin beads. The vessels are equipped with a **PTFE-lined ground glass joint** (24/40 standard taper), allowing for secure, leak-proof connections with compatible adapters, syringes, or other glassware, while the PTFE lining prevents corrosion and ensures compatibility with a wide range of solvents, including DMF, DCM, and TFA. The robust construction of the vessels, reinforced with a sturdy neck and base, resists thermal shock and mechanical impact, making them suitable for use in both manual and automated synthesis setups. Additionally, the transparent borosilicate glass enables real-time monitoring of reaction progress, color changes, and resin bed uniformity, enhancing workflow efficiency. Whether employed for routine peptide synthesis, scale-up processes, or specialized applications such as native chemical ligation or combinatorial chemistry, these vessels deliver reliability, precision, and ease of use making them an indispensable tool for researchers and laboratories focused on peptide chemistry.
**Pros and Cons of Buying Chemglass CG-1860-05 and CG-1860-15 Glass Frit Solid Phase Peptide Synthesis Vessels**
### **Pros**
1. **High-Quality Glass Construction**
- Made from borosilicate glass, which is chemically resistant, durable, and compatible with a wide range of solvents and reagents used in peptide synthesis. This minimizes contamination risks and ensures long-term usability.
2. **Optimal Design for Solid Phase Peptide Synthesis (SPPS)**
- The frit design allows for efficient filtration and washing without losing resin beads, which is critical in SPPS for maintaining yield and purity. The frit prevents resin from clogging the outlet while still allowing solvent flow.
3. **Scalability**
- The CG-1860-05 (500 mL) and CG-1860-15 (1.5 L) models cater to different batch sizes, making them versatile for both small-scale research and larger-scale synthesis. This flexibility is valuable for growing labs or projects requiring variable volumes.
4. **Compatibility with Standard SPPS Procedures**
- The vessels are designed to work seamlessly with common SPPS protocols, including coupling, deprotection, and cleavage steps. Their robust construction ensures they can withstand repeated use and harsh conditions (e.g., acidic or basic washes).
5. **Easy to Clean and Maintain**
- Borosilicate glass is non-porous and resistant to organic solvents, making it straightforward to clean between uses. The smooth interior reduces the risk of residue buildup, which can be problematic with plastic or less durable materials.
6. **Durability and Longevity**
- Unlike plastic or disposable alternatives, these vessels are built to last for years with proper care. This makes them a cost-effective investment over time, especially for labs performing frequent peptide synthesis.
7. **Compatibility with Vacuum Systems**
- The design supports vacuum filtration, which is essential for efficient washing and solvent removal during SPPS. This feature speeds up synthesis cycles and improves overall workflow efficiency.
8. **Brand Reputation**
- Chemglass is a well-established manufacturer known for high-quality laboratory glassware. Their products are widely trusted in academic and industrial settings for reliability and performance.
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### **Cons**
1. **Higher Initial Cost**
- Compared to disposable or lower-quality plastic alternatives, these glass vessels are more expensive upfront. This may be a barrier for small labs or individual researchers on tight budgets.
2. **Fragility Compared to Plastic**
- While borosilicate glass is durable, it is still more fragile than plastic. Dropping or mishandling the vessel could lead to breakage, which may be a concern in busy or less controlled lab environments.
3. **Weight and Portability**
- Glass vessels are heavier than plastic ones, which can make them less convenient to transport or store. This may be an issue in labs with limited bench space or where mobility is required.
4. **Potential for Scratches or Damage Over Time**
- Despite their durability, repeated use with abrasive reagents or improper cleaning techniques (e.g., using metal tools) can scratch the glass surface. While this does not typically affect functionality, it may impact aesthetics or future resale value.
5. **Requires Proper Care to Avoid Contamination**
- Glass vessels must be thoroughly cleaned and dried after each use to prevent cross-contamination between different peptide synthesis runs. Neglecting this step could compromise the integrity of subsequent experiments.
6. **Limited Availability of Replacement Parts**
- If the frit or other internal components become damaged, finding replacements may be difficult or costly. This is less of an issue with the vessel itself but could be a concern for long-term users.
7. **Not Ideal for High-Pressure Applications**
- While these vessels are designed for standard SPPS conditions, they are not suitable for high-pressure or extreme temperature applications. Researchers working under such conditions would need alternative equipment.
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### **Conclusion**
The Chemglass CG-1860-05 (500 mL) and CG-1860-15 (1.5 L) glass frit vessels are excellent choices for researchers and labs engaged in solid phase peptide synthesis. Their superior durability, chemical resistance, and efficient filtration capabilities make them indispensable for high-quality peptide production. While the upfront cost and fragility are drawbacks, the long-term reliability, cost-effectiveness, and performance advantages far outweigh these minor limitations for most users.
For labs prioritizing quality, reproducibility, and scalability, these vessels are highly recommended. They are particularly well-suited for academic research, pharmaceutical development, and industrial applications where consistency and durability are critical.
### **Recommendation**
If your budget allows and you require a durable, high-performance vessel for SPPS, investing in the Chemglass CG-1860 series is a wise choice. For small-scale or occasional use, consider evaluating the cost-benefit ratio against disposable alternatives. However, for serious peptide synthesis work, the benefits of glassware such as longevity, chemical compatibility, and filtration efficiency make it the preferred option. Always ensure proper handling and maintenance to maximize their lifespan and performance.
Details:
GSR veers 1730 GS 9.9.4 1730 Used item in great condition. See pictures for details. No chips or cracks throughout.
part #: cg186005 price
- $84.74
specifications plasticwarelabsuppy:
- brand: Chemglass
- mpn: Cg-1860-05
- intended use/discipline: Biological Laboratory, Dental Laboratory, Medical Laboratory, Microbiological Laboratory, Physical Laboratory
- unit type: Unit
- country of origin: United States
- additional information: Surplus Laboratory Consumable Supplies
seller plasticwarelabsuppy:
- rating: 99.8%
- # reviews: 7421
- city: Cotati, California
offer plasticwarelabsuppy:
- options: Ship-to-home
- availability: In Stock
- started: February 13, 2026
- sold: 0
- quantity: 1
shipping plasticwarelabsuppy:
- cost: $0.00
- carrier: FedEx
- transit: 6-13 Days
- service: Standard, FedEx 2Day, FedEx Standard Overnight
- class: Standard, Expedited, One-day
- type: Fixed
returns plasticwarelabsuppy:
- time: 30 Days
- policy: Returns Accepted
- paid by: Seller
- method: Money back
payments plasticwarelabsuppy:
- credit card: Mastercard
- other
- wallet: Google-pay
general plasticwarelabsuppy:
- Medical, Lab Dental Supplies > Glassware Plasticware > Other Medical Lab Glassware
- condition: Used
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