
( Brand: Fisher Scientific ), ( Manufacturer Part Number: 12565502 ), ( Part Type: Plate )
The Fisher Scientific 12565502 Round Bottom 96-Well Plate is a high-performance, precision-engineered tool designed for demanding laboratory applications, particularly in high-throughput screening, biochemical assays, and automated liquid handling workflows. Crafted from high-quality, transparent polystyrene, this plate features a distinctive round-bottom design that optimizes mixing efficiency and minimizes dead volume, ensuring consistent and reliable results across all wells. The smooth, uncoated surface promotes uniform distribution of reagents and samples, reducing the risk of adsorption or non-specific binding, which is critical for accurate experimental outcomes. Each well is precisely calibrated to a volume capacity of 1.2 mL, providing ample space for a wide range of assays while maintaining compatibility with standard multi-channel pipettes and robotic liquid handling systems. The plate s robust construction, reinforced with a durable, flat-bottomed base, enhances stability during centrifugation and shaking procedures, further safeguarding sample integrity. Additionally, the transparent material allows for easy visualization of reactions, colorimetric endpoints, or fluorescence signals without the need for additional instrumentation, streamlining qualitative assessments. Whether used in drug discovery, molecular biology, or analytical chemistry, this plate excels in environments requiring both precision and versatility, offering a seamless integration into automated workflows while delivering consistent, reproducible data. Its compatibility with a broad spectrum of detection methods including absorbance, fluorescence, and luminescence makes it an indispensable asset for laboratories seeking to maximize efficiency and accuracy in their research endeavors.
### **Pros and Cons of Buying Fisher Scientific 12565502 (96-Well Round Bottom Plate)**
#### **Pros:**1. **High-Quality Material** Made from polypropylene, which is durable, chemically resistant, and suitable for a wide range of laboratory applications, including centrifugation, freezing, and chemical treatments.
2. **Standardized Dimensions** Complies with common labware standards (96-well format), ensuring compatibility with most automated liquid handlers, pipettes, and microplate readers.
3. **Round Bottom Design** Facilitates efficient mixing and settling of precipitates, reducing dead volume and improving assay performance in applications like ELISA, PCR, and cell culture.
4. **Automation-Friendly** Designed to work seamlessly with robotic systems, reducing manual handling and improving workflow efficiency in high-throughput labs.
5. **Sterile and Low-Binding** Some variants (if purchased sterile) minimize protein or DNA adsorption, which is beneficial for sensitive assays.
6. **Wide Application Range** Suitable for molecular biology, cell culture, biochemical assays, and other lab techniques requiring precise liquid handling.
7. **Brand Reliability** Fisher Scientific is a trusted supplier with consistent quality control, reducing the risk of defects or performance issues.
8. **Cost-Effective for Bulk Use** While individual plates may seem expensive, purchasing in bulk can reduce per-unit costs, making it economical for large-scale labs.
#### **Cons:**1. **Higher Upfront Cost** Compared to generic or lower-end alternatives, Fisher Scientific products are premium-priced, which may be a barrier for small labs or budget-conscious users.
2. **Potential Overkill for Simple Tasks** If the lab only performs basic assays (e.g., simple ELISA or cell counting), a less expensive generic plate may suffice without sacrificing performance.
3. **Limited Customization** Unlike some specialty plates, this product does not offer additional features like color-coded wells, adhesive strips, or specialized coatings unless specified in a variant.
4. **Disposal Considerations** Polypropylene plates are not biodegradable, and improper disposal may contribute to lab waste management challenges.
5. **Compatibility Issues with Some Equipment** While generally compatible, certain older or non-standard lab equipment might not fit perfectly, requiring adapters or adjustments.
6. **Potential for Contamination** If not stored properly (e.g., exposed to dust or chemicals), the plates could become contaminated before use, requiring additional cleaning or replacement.
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### **Conclusion**
The **Fisher Scientific 12565502 96-Well Round Bottom Plate** is a high-quality, versatile tool ideal for labs requiring precision, automation compatibility, and durability. Its advantages in mixing efficiency, chemical resistance, and standardization make it a strong choice for molecular biology, cell culture, and high-throughput applications. However, the higher cost and potential over-specification for simpler tasks may not justify the purchase for all labs.
For **research labs, biotech facilities, or institutions with automation needs**, this plate is a reliable investment. For **smaller labs, educational settings, or cost-sensitive environments**, evaluating generic alternatives or lower-cost brands (while ensuring compatibility) may be more practical.
### **Recommendation:**- **Buy if:** You need a durable, standardized plate for automation, high-throughput assays, or applications requiring efficient mixing (e.g., PCR, ELISA, cell culture). Justify the cost by purchasing in bulk or through institutional discounts.
- **Consider alternatives if:** Your budget is tight, or you only require basic functionality. Explore lower-cost generic plates (e.g., from Corning or USA Scientific) that meet your specific needs without sacrificing quality.
- **Verify compatibility:** Ensure your lab equipment (pipettes, readers, centrifuges) supports this plate format before committing to purchase.
Fisher Scientific Round Bottom 96 Well Plate 12565502, 10/PK, total 20 plates in two packs.